89. Jahrestagung der Deutschen Gesellschaft für Kardiologie

Freitag, 14. April 2023 (Posterbereich 25) 10:00-11:30

Postervorträge

Mechanisms in transcriptional regulation

Diskussionsleitung: R. P. Brandes (Frankfurt am Main), G. Euler (Gießen)

(P1362) Clonal hematopoiesis associated TET2 and DNMT3A gene driver mutations accelerates aortic valve calcification in vitro and in vivo
    W. Abplanalp, B. Schuhmacher, S. Mas-Peiro, J. Fuster, M. Shumliakivska, D. John, M. Nicotera, M. Merten, S. Dimmeler, A. M. Zeiher (Frankfurt am Main; 28029, ES)
(P1363) Clonal hematopoiesis driven by DNMT3A mutations promotes cardiac interstitial fibrosis via EGFR signaling pathway in heart failure
    M. Shumliakivska, G. Luxan, W. Abplanalp, B. Schuhmacher, A. Debes, V. Puntmann, J. Hoffmann, E. Nagel, I. Hemmerling, F. Leuschner, S. Cremer, A. M. Zeiher, S. Dimmeler (Frankfurt am Main, Heidelberg)
(P1364) ADAR2 represses circRNA formation in the human heart
    K. E. Kokot, J. M. Kneuer, D. John, S. Rebs, M. Möbius-Winkler, S. Erbe, M. Müller, M. Andritschke, S. Gaul, B. Sheikh, J. Haas, H. Thiele, O. J. Müller, S. Hille, F. Leuschner, S. Dimmeler, K. Streckfuß-Bömeke, B. Meder, U. Laufs, J.-N. Boeckel (Leipzig, Frankfurt am Main, Würzburg, Bad Oeynhausen, Heidelberg, Kiel)
(P1365) Comparative proteomic analysis of human heart tissue of over 100 patients undergoing heart transplantation
    U. Resch, L. M. Schmidt, M. Saynisch, S. Müller, J.-W. Lackmann, S. Baraktar, V. Schmidt, M. Hayungs, L. Görtz, U. Boeken, A. Lichtenberg, M. Krueger, E. Weber, H. Aubin (Düsseldorf, Köln)
(P1366) Posttranslational modified (glycated) lysins and arginins in core histones in aging human heart / endothelial cells: impact on histone octamer and nucleosome stability
    S. Karande, A. Urazova, T. Gruber, J. Balbach, G. Szabó, A. Simm (Halle (Saale))
(P1367) Fibrotic signaling promotes heart failure progression through SOX9 mediated chromatin remodeling in cardiomyocytes
    G. M. Dittrich, H. Mitseva, R. Wardman, F. A. Trogisch, A. Schober, S. Grein, J. Cordero, G. Dobreva, J. Heineke (Mannheim)
(P1368) Epigenetic aging and global and regional DNA methylation in the development and progression of heart failure
    M. Krolevets, V. ten Cate, J. Prochaska, A. Schulz, S. Rapp, S. Horvath, C. Niehrs, P. S. Wild (Mainz; San Diego, US)
(P1369) Identification and functional epigenetic modulation of regulatory elements in cardiac myocytes
    P. Laurette, C. Cao, M. Schwaderer, N. Díaz i Pedrosa, R. Bednarz, L. Weiss, F. Rezende, D. P. Ramanujam, S. Engelhardt, R. Gilsbach (Heidelberg, Freiburg im Breisgau, Frankfurt am Main, München)