Abstract 920 The impact of body-mass-index on the outcome of patients suffering from myocardial infarction with non-obstructive coronary artery disease

Clin Res Cardiol (2023). https://doi.org/10.1007/s00392-023-02180-w
The impact of body-mass-index on the outcome of patients suffering from myocardial infarction with non-obstructive coronary artery disease
I. El-Battrawy¹, C. Schlettert¹, M. Behnes², M. Abumayyaleh², I. Akin², A. Mügge³, A. Aweimer¹
¹Medizinische Klinik II, Kardiologie und Angiologie, Berufsgenossenschaftlliches Universitätsklinikum Bergmannsheil, Bochum; ²I. Medizinische Klinik, Universitätsklinikum Mannheim, Mannheim; ³Medizinische Klinik II, Kardiologie, Klinikum der Ruhr-Universität Bochum, Bochum;
Background Several studies reported on baseline characteristics and outcome of patients suffering from myocardial infarction with non-obstructive coronary disease (MINOCA). The impact of body-mass-index (BMI) on the outcome of patients has not been studied yet. Methods Clinical data were screened for patients admitted at the Bergmannsheil University Medical Center from 2010 to 2021 with an elevated troponin-level. 6000 patients received a coronary angiography. All patients suffering from myocardial infarction with MINOCA were included. Among 6000 cases 374 patients fulfilled the criteria. Three ranges of body-mass-index (BMI) were identified <25, 25-30 and >30 kg/m². Results 374 patients (62.9+15.9, 49.5% males) were identified in the clinic database. The age was similar in the three BMI groups. Male gender was highest presented in the mid-BMI-group (39.7% versus 55.3% versus 52.7%; p=0.02). The duration of hospitalization was longest in the BMI group<25 kg/m² (11.8+11 days versus 8.6+6 days versus 10.1+7 days; p=0.01). Diabetes mellitus was significantly higher presented in the BMI group>30 kg/m² (8.3% versus 12.8% versus 33.3%; p<0.001). Other cardiovascular risk factors were similar presented in each group. At admission BMI>30 kg/m² suffered significantly more from dyspnea (46.6% versus 35.5% versus 53.6%; p=0.013). At admission malignant arrhythmias and atrial fibrillation showed a similar rate in each group. In addition, the left ventricular ejection fraction did not differ significantly between the groups (52.4+14.6% versus 50.7+14% versus 49.1+14%; p=0.33). During in-hospital stay all groups suffered a similar rate of cardiovascular complications e.g. LV thrombus, stroke, thromboembolic events, cardiogenic shock, cardiopulmonary resuscitation and mechanical ventilation. But nevertheless, the BMI>30 kg/m² group suffered more significantly from ventricular tachyarrhythmias (0% versus 0.7% versus 2.7%; p=0.04). The in-hospital mortality did not differ significantly between the groups. Conclusions Among MINOCA patients a BMI>30 kg/m² may present a high-risk group with a higher rate of ventricular tachyarrhythmias.
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