Clin Res Cardiol (2023). https://doi.org/10.1007/s00392-023-02180-w

Feasibility and efficacy of transcatheter tricuspid valve repair using Edge-to-Edge-Technique in patients with cardiac implantable electric devices
M. N. Alachkar1, B. Salloum1, H. Mady1, O. Bisht1, M. Cheikh-Ibrahim1, L. Krygier1, C. Mahnkopf1, S. Schnupp1
1II. Medizinische Klinik - Kardiologie, Angiologie, REGIOMED-KLINIKEN GmbH, Coburg;

Background: Transcatheter tricuspid valve repair using the Edge-To-Edge-Technique (TEER) has emerged as an alternative therapy in patients with severe tricuspid regurgitation (TR) and high surgical risk. This retrospective, single-centre study aims to evaluate the feasibility and efficacy of tricuspid valve TEER in patients with cardiac implanted electric devices (CIEDs).

Methods: All patients who underwent tricuspid valve TEER at our centre were retrospectively screened. Patients with CIEDs were included. Procedure success was defined as implantation of at least one clip and reduction of TR of at least one grade. Success of procedure and intrahospital outcome (MACE) were evaluated.

Results: 96 patients underwent TEER. Of them 11 patients had CIEDs. (Age 80±6 years, male=7). 6 patients had a pacemaker, 2 patients had an ICD, and 3 patients had a CRT-system. Median time from device implantation to TEER was 132 months (IQR 41-180 months). Success of the procedure was achieved in 10 patients (91%) with reduction of TR grade from 3.7±0.7 to 1.6 ±0.7, p< 0.01 (figure 1). Intrahospital mortality occurred in 1 patient due to progressive renal failure.  No other intrahospital MACE were observed. No CIEDs related adverse events were observed. Procedural data are provided in table 1.

Conclusions: Our single centre experience suggests that transcatheter tricuspid valve repair using Edge-To-Edge-Technique (TEER) seems to be feasible and efficient in patients with CIEDs.

Table 1. Procedural data and intrahospital outcome.

Procedural data

 

Success of procedure, n (%)

10 (91)

Numbers of implanted clip pro patient

 

1 clip, n (%)

8 (80)

2 clips, n (%)

2 (20)

Position of clip

 

Antero-septal

7 (70)

Postero-septal

3 (30)

Both

0

Intrahospital outcome

 

MACE, n (%)

1 (9)

CIEDs related adverse events

0 (0)

 

Figure 1. Comparison of TR severity before and after TEER





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