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(P471) |
Hyperhomocysteinemia potentiates monocyte activation through the methylation-dependent dysregulation of PTEN phosphatase function |
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M. Dorenkamp, D. Semo, L. Miao, S. Koch, H. Reinecke, R. Godfrey (Münster) |
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(P472) |
Involvement of LXRβ signalling in the pathogenesis of aortic valve stenosis and prevention by saringosterol |
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M. Nöthel, A. Schmidt, M. T. Mulder, T. Vanmierlo, S. Friedrichs, S. V. Schmidt, G. Voortman, P. R. Goody, S. Zimmer, G. Nickenig, D. Lütjohann, J. Jehle (Bonn, Hasselt; Rotterdam, NL) |
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(P473) |
Insulin-like Growth Factor 1, but not Insulin, Polarizes Macrophages to an anti-Inflammatory Phenotype by Jak/Stat Activation |
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A. Spychala, R. Nederlof, S. Reidel, P. Petzsch, K. Köhrer, A. Gödecke (Düsseldorf) |
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(P474) |
Effect of secreted modular calcium binding protein 1 (SMOC1) and soluble epoxide hydrolase (sEH) on macrophage polarization |
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Ü. Ukan, X. Li, F. A. Delgado Lagos, I. Fleming (Frankfurt am Main, 60590) |
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(P475) |
In vitro conditions of uremia induce differentiation of aortic valvular interstitial cells to a pro-calcific phenotype |
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P. Düsing, M. R. Hosen, P. R. Goody, G. Nickenig, A. Zietzer, F. Jansen (Bonn) |
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(P476) |
Adverse effects of pro-inflammatory cytokines on cell-cell contacts in healthy and plakophilin-2 deficient hiPSC-cardiomyocytes |
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K. Walz, A. Janz, A. Cirnu, A. Kroth, J. Surjanto, B. Gerull, für die Studiengruppe: DZHI (Würzburg) |
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(P477) |
Clonal hematopoiesis–driver DNMT3A mutations induce pro-inflammatory phenotype in macrophages and enhance macrophage-to-fibroblast interaction in the failing human heart |
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M. Shumliakivska, W. Abplanalp, G. Luxan, B. Schuhmacher, R. Schulze Bruening, D. John, S. Cremer, A. M. Zeiher, S. Dimmeler (Frankfurt am Main) |