Clin Res Cardiol (2022). https://doi.org/10.1007/s00392-022-02002-5

Evaluation of right atrial function by two-dimensional speckle-tracking echocardiography in patients with RCA CTO PCI
R. Blessing1, M. Ahoopai1, M. Geyer2, S. Steven3, A. M. Zeiher4, M. Vasa-Nicotera4, I. Drosos2, T. Münzel2, P. Wenzel3, T. Gori3, Z. Dimitriadis4
1Zentrum für Kardiologie, Kardiologie I, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz; 2Kardiologie 1, Zentrum für Kardiologie, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz; 3Zentrum für Kardiologie, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz; 4Med. Klinik III - Kardiologie Zentrum der Inneren Medizin, Universitätsklinikum Frankfurt, Frankfurt am Main;

Objectives: Coronary chronic total occlusion (CTO) are encountered in about 15-25% of patients with coronary artery disease undergoing coronary angiography. After neutral findings, recent evidence has demonstrated several benefits after successful CTO revascularization, especially in terms of angina relief and myocardial ischemia reduction. The impact of successful CTO PCI on cardiac function is incompletely understood. Here, atrial function has not been investigated yet. In our study, we aimed to evaluate atrial function after successful RCA CTO PCI using transthoracic echocardiography with additional strain assessment.

Methods & Results: At the University Medical Center in Mainz 60 patients were included in the study. We evaluated demographic, clinical, angiographic, and periprocedural information. Right atrial strain was assessed before and 6 months after successful RCA CTO PCI. The median age of the total collective was 67 (30-90) years. We did not find difference in our analysis of RA Volume (p 0.079), RA area (p 0.05), RA length (p 0.1) and RA diameter (p 0.42) at baseline and follow-up.

Mean RA reservoir strain at baseline was 25.6± 9.4 and 27.9± 11.0 in follow up (p 0.03). Mean RA conduit strain was 15.9± 7.1 at baseline and 16.4± 6.7 (p 0.48) in follow-up. Mean RA contraction strain was 9.8± 6.6 at baseline and 12.0± 6.6 at follow-up (p 0.01).

Conclusion: RA conduit strain and RA contraction strain was increased in patients with RCA CTO. We find an improvement of RA strain parameters after successful RCA CTO PCI.


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