Methods:
Among 295 patients who underwent RA between 01.2010 and 02.2019 at a single center, 49 developed CI-AKI. Those who were on chronic haemodialysis or with no available 48-hours′ kidney function tests were excluded. Predictors of CI-AKI were assessed in the whole cohort and in those with no basal renal impairment.

Results:
The rate of CI-AKI was 16.6%. The tvSS was 18 [14-23] vs. 12 [9-18] in patients with vs. without CI-AKI (p<0.001). The tvSS cut-off value of 15 provided 75% sensitivity and 60% specificity for predicting CI-AKI. Consequently, a tvSS ≥15 emerged as an independent pre-procedural predictor for CI-AKI (adjusted OR: 4.94, 95% CI: 2.38-10.20, p<0.001), along with left ventricular ejection fraction (LVEF) ≤35% (p=0.016) and glomerular filtration rate (GFR) <45 ml/min (p=0.004). TvSS was the only independent pre-procedural predictor for CI-AKI in patients with GFR ≥60 ml/min (p<0.001). The contrast volume/GFR ratio and peri-procedural myocardial infarction (MI) were independent procedural predictors for CI-AKI in the whole cohort and in patients with basal GFR ≥60 ml/min.

Conclusion:
CI-AKI after RA is frequent. The tvSS is an efficient pre-procedural predictor for CI-AKI after RA, along with LVEF ≤35% and GFR <45 ml/min. Contrast volume/GFR ratio and peri-procedural MI emerged as procedural predictors for CI-AKI.