Clin Res Cardiol (2022). https://doi.org/10.1007/s00392-022-02002-5
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Outcomes of transcatheter aortic valve implantations requiring a surgical bailout in Germany
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V. Oettinger1, M. Zehender1, C. Bode1, C. von zur Mühlen1, K. Kaier2, D. Dürschmied3, P. Stachon3, für die Studiengruppe: CeBAC
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1Innere Medizin III, Kardiologie und Angiologie, Universitätsklinikum Freiburg, Freiburg im Breisgau; 2Institut für Medizinische Biometrie und Statistik, Universitätsklinikum Freiburg, Freiburg im Breisgau; 3I. Medizinische Klinik, Universitätsklinikum Mannheim, Mannheim;
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Background: Major
complications during transcatheter aortic valve implantation (TAVI) can force a
surgical bailout, but little is known about the resulting outcomes in Germany.
Methods: Using German national
records, all TAVI between 2007 and 2019 were identified, with focus on 2018 and
2019. Furthermore, those procedures requiring surgical bailout were extracted.
Results: A total of 136,671 patients received
TAVI. Overall rate of surgical bailout was 2.58% and overall in-hospital
mortality 4.11%. In-hospital mortality after surgical bailout was 16.04%. While
the annual number of procedures in all TAVI rose steeply (202 to 22,419), the
rate of surgical bailout dropped from 27.23 to 0.69% and that of overall
mortality from 11.39 to 2.50%. However, mortality in case of surgical bailout
remained high with 26.45% in 2019. After risk adjustment, in 2018 and 2019, standardized
rates of overall in-hospital mortality and surgical bailout for both
balloon-expandable and self-expanding transfemoral TAVI were significantly
lower than for transapical TAVI (transapical vs transfemoral
balloon-expandable vs self-expanding TAVI: in-hospital mortality: 5.38% [95% CI
4.43;6.33] vs 2.43% [2.12;2.75] vs 2.39% [2.11;2.67]; surgical bailout: 2.43%
[1.67;3.19] vs 0.83% [0.61;1.05] vs 0.45% [0.33;0.58]). Main risk factors for
surgical bailout were coronary artery disease (risk adjusted OR=1.44
[1.12;1.85], p=0.005) and higher grade heart failure NYHA III/IV (OR=1.42
[1.09;1.85], p=0.010).
Conclusion: Rates of
TAVI requiring a surgical bailout as well as overall in-hospital mortality drop
substantially over the years. However, in case of surgical bailout, the
outcomes remain poor with consistently high in-hospital mortality.
Figure: Standardized rates of
in-hospital mortality and surgical bailout for TAVI in 2018 and 2019
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https://dgk.org/kongress_programme/jt2022/aP1595.html
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