Clin Res Cardiol (2021). 10.1007/s00392-021-01933-9

Percutaneous coronary intervention for chronic total occlusion in octogenarians a propensity score study
R. Blessing1, M. Brandt1, M. Geyer1, T. Gori2, P. Wenzel2, T. Münzel1, M. Ahoopai1, M. Vasa-Nicotera3, A. M. Zeiher3, Z. Dimitriadis3
1Kardiologie 1, Zentrum für Kardiologie, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz; 2Zentrum für Kardiologie, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz; 3Med. Klinik III - Kardiologie Zentrum der Inneren Medizin, Universitätsklinikum Frankfurt, Frankfurt am Main;
The study investigated the feasibility and effect of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) in octogenarians, a more frail population due to more comorbidities in comparison to non-octogenarians. We compared success and complication rate of CTO PCI between these two collectives. To compare the results we calculated the propensity score and used inverse probability of treatment weighting (IPTW).  Data from 267 patients (58 patients over 80 years of age and 209 under 80 years of age) who had undergone CTO PCI were analyzed. We evaluated demographic, clinical, angiographic, and periprocedural information. The median age of the total collective was 68 (31-90) years (octogenarian collective 82 (80-90) years vs non-octogenarians 65 (31-79) years). We observed a high success rate in both collectives (82.8% vs 90.4%, p= 0.1) and no difference in periprocedural complications or complications in the follow-up period. In our collective we found a comparable restenosis rate at follow-up (11.3% vs 16.3%, p= 0.9). Our results show that CTO PCI in older patients is safe and feasible with comparable in-hospital and follow-up complication rates compared to a younger patient population.

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