Clin Res Cardiol (2021). 10.1007/s00392-021-01933-9

Impairment of Quality of Life in Patients with subcutaneous Cardioverter Defibrillator (S-ICD) compared to transvenous Cardioverter Defibrillator Therapy: A Preliminary Study
M. Haum1, M. Thienel1, S. Sadoni2, J. Novotny1, H. L. Estner3, S. Fichtner1, K. Lackermair1
1Medizinische Klinik und Poliklinik I, LMU Klinikum der Universität München, München; 2Herzchirurgische Klinik und Poliklinik, LMU Klinikum der Universität München, München; 3Med. Klinik u. Poliklinik, Interventionelle Elektrophysiologie, LMU Klinikum der Universität München, München;

ABSTRACT

Background

The subcutaneous cardioverter defibrillator (S-ICD) has been shown to be a viable alternative to transvenous ICDs (TV-ICD) in all patients at risk of sudden cardiac death (SCD) but without pacing indication. However, the impact of therapy with current S-ICD devices on quality of life (QoL) has not been studied yet.

Methods

In our single-centre study, 52 consecutive patients with S-ICD and 52 matched patients with TV-ICD were analysed. QoL has been assessed by a standardized questionnaire (EQ-5D-3L, modified). Additionally, clinical baseline and follow-up data were evaluated.

Results

Two-thirds of the total study population reported of restrictions in daily routine compared to their life before ICD implantation. 27.7% of S-ICD patients stated to expect an improvement of QoL by deactivation or explantation of their defibrillator compared to only 6.4% of patients with TV-ICD (p=0.006), which was mainly caused by discomfort and pain from the S-ICD pocket (relevant discomfort and pain in 32.6 vs. 11.5%; p<0.01).

Conclusions

A relevant part of S-ICD patients expects an improvement of QoL by explantation of the device. Of note, this impression was not driven by the fear of receiving shocks but mainly by discomfort and pain caused by the pulse generator.


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