Basic science: Tonusregulation der Gefäße bei Inflammation und oxidativem Stress
Vorsitz: A. El-Armouche (Dresden), E. Schwedhelm (Hamburg)
(V41) | A novel oxidant sensor in the cGMP-binding pocket of PKGIα regulates second messenger-mediated kinase activity | |
M. Goetz, S. Donzelli, K. Schmidt, M. Wolters, K. Stathopoulou, O. Prysyazhna, J. Scotcher, H. Subramanian, E. Butt, V. Nikolaev, C. de Wit, L. Leichert, R. Feil, P. Eaton, F. Cuello (Hamburg, Lübeck, Tübingen, Würzburg, Bochum; London, UK) | ||
Diskussion | ||
(V42) | Sex-specific expression of β-adrenoceptors in macrovessels | |
I. Kopaliani, S. Al-Gburi, B. Zatschler, S. Weber, A. El-Armouche, K. Lorenz, M. Cybularz, H. Morawietz, A. Deussen (Dresden, Dortmund) | ||
Diskussion | ||
(V43) | Suppression of endothelin-1 signaling by macitentan improves isosorbide-5-mononitrate (ISMN) and isosorbide dinitrate (ISDN) induced endothelial dysfunction, oxidative stress and vascular inflammation | |
S. Steven, M. Oelze, S. Roohani, F. Kashani, M. Hausding, S. Kröller-Schön, E. Schulz, T. Münzel, A. Daiber (Mainz) | ||
Diskussion | ||
(V44) | VEGF-induced septic hyperpermeability is mediated by the VEGFR-adaptor TSAd | |
T. Ziegler, M. Asadi, D. Bongiovanni, S. d'Almeida, T. Zhang, R. Hinkel, M. Hellström, K.-L. Laugwitz, C. Kupatt (Munich, München; Uppsala, SE) | ||
Diskussion | ||
(V45) | Conditional knockout of heme oxygenase-1 in lysozyme M positive cells attenuates angiotensin II induced vascular inflammation | |
J. Lagrange, S. Kossmann, T. Münzel, P. Wenzel (Mainz) | ||
Diskussion | ||
(V46) | Sphingolipids improve vascular barrier function and systemic blood pressure by reducing pericyte loss during LPS-mediated inflammation | |
T. Ziegler, F. Abdel Rahman, T. Zhang, S. d'Almeida, R. Hinkel, K.-L. Laugwitz, C. Kupatt (Munich, München) | ||
Diskussion |
15:00 - 15:30 | P a u s e |