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(P1402) |
HIF-mediated upregulation of lncRNA H19 under hypoxic conditions improves cardiomyocyte cell survival |
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L. Peuker, J. Viereck, F. Kenneweg, A. Foinquinos, S. Batkai, T. Thum (Hannover) |
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(P1403) |
LNA92a application leads to mir92a inhibition and is cardioprotective in a pig model of hibernating myocardium |
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K. Klett, V. Kaczmarek, R. Hinkel, A. Fischer, A. Howe, A. M. Zeiher, S. Dimmeler, C. Kupatt (München, Frankfurt am Main) |
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(P1404) |
Anti-fibrotic effects of Finerenone – a novel non-steroidal mineralocorticoid receptor antagonist in a model of isoprenaline-induced cardiomyopathy |
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J. Grune, E. Smeir, N. Beyhoff, A. Blumrich, Z. Ban, S. Brix, I. Betz, B. Höft, A. Foryst-Ludwig, R. Klopfleisch, P. Stawowy, P. Kolkhof, U. Kintscher (Berlin, Wuppertal) |
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(P1405) |
Regional LNA-132 application inhibits miR-132 expression and prevents hypertrophy-induced cardiomyopathy in pigs |
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K. Klett, R. Hinkel, S. Straub, A. Howe, S. Batkai, A. Foinquinos, R. Kozlik-Feldmann, T. Thum, C. Kupatt (München, Hannover, Hamburg) |
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(P1406) |
Natural compound library screen in vitro identifies potent molecules with anti-fibrotic activity through modulation of noncoding RNAs |
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K. Schimmel, K. Bock, L. Grote-Levi, S. Batkai, J. Fiedler, K. Xiao, R. Geffers, Q.-T. Do, J. H. Bräsen, T. Thum (Hannover, Braunschweig; Orléans, FR) |
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(P1407) |
LUMA encoded by the gene TMEM43 is a nuclear rim protein and its membrane mobility is not affected by the deleterious Newfoundland mutation p.S358L |
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D. Baurichter, A. Gärtner-Rommel, B. Klauke, D. Anselmetti, J. Gummert, H. Milting (Bad Oeynhausen, Bielefeld) |