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(P741) |
AMPK deletion in myeloid-cells enhances myocardial ROS production and inflammation after Doxorubicin treatment leading to impaired systolic LV function |
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T. Jansen, E. Schulz, A. Daiber, T. Münzel (Mainz) |
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(P742) |
Does diastolic sarcoplasmic reticulum calcium leak have any role in heart failure progression after chronic biomechanical stress in mice? |
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B. A. Mohamed, S. Khadjeh, S. T. Sossalla, S. Neef, S. Lehnart, G. Hasenfuß, K. Toischer (Göttingen) |
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(P743) |
Iron deficiency in cardiac myocytes promotes cardiac dysfunction in experimental heart failure |
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S. Haddad, Y. Wang, M. Korf-Klingebiel, A. M. Baru, U. Flögel, S. Engeli, J. Jordan, D. Fraccarollo, J. Bauersachs, K. Toischer, G. Hasenfuß, B. Galy, M. W. Hentze, K. C. Wollert, T. Kempf (Hannover, Düsseldorf, Göttingen, Heidelberg) |
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(P744) |
Interhelical interaction and receptor phosphorylation determine the efficacy of the common Arg389-variant of the human beta1-adrenoceptor |
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A. Ahles, F. Rodewald, F. Rochais, M. Bünemann, S. Engelhardt (München, Würzburg, Marburg) |
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(P745) |
Role of Liver X Receptors in Cardiac Energy Metabolism and Heart Failure |
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T. Zoergiebel, C. Köhncke, P. Lacour, N. Huebner, A. Heuser, J. Drenckhahn, M. Jastroch, H. Uhlenhaut, S. Kempa, F. Blaschke (Berlin, Neuherberg) |
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(P746) |
Effects of MR activation on contractility and Ca2+ cycling in rat cardiomyocytes of endo- and epicardial origin |
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M. Wagner, C. Wacker, N. Dams, T. Volk (Dresden, Erlangen) |
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(P747) |
Impaired sarcolemmal and sarcoplasmic reticulum calcium handling in atrial myocytes during early hypertension and left ventricular hypertrophy in rats |
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F. Pluteanu, Y. Nikonova, J. Plackic, J. Preisenberger, A. Rinne, M.-C. Kienitz, J. Kockskämper (Marburg, Bochum) |
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(P748) |
PAC1 receptor agonist Maxadilan enhances calcium transients in rat atrial myocytes via protein kinase A-mediated increase in fractional SR calcium release |
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S. Healy, J. Preisenberger, F. Pluteanu, E. Weihe, J. Kockskämper (Marburg) |
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(P749) |
Enhancement of cardiac maturation in stem cell-derived cardiomyocytes by patterned growth |
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S. Wantha, T. Autenrieth, M. Hecker, M. Bastmeyer, N. Ullrich (Heidelberg, Karlsruhe) |
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(P750) |
Alterations in calcium handling in atrial myocytes from old hypertensive rats during transition from compensated left ventricular hypertrophy to heart failure |
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F. Pluteanu, A. Holzapfel, Y. Nikonova, T. Ivanova, J. Preisenberger, B. Herzog, J. Plackic, J. Kockskämper (Marburg) |
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(P751) |
Constitutively active phosphatase inhibitor-1 improves cardiac contractility in unchallenged mice but is deleterious in a model of pressure-overload |
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D. Schwab, R. Bauer, L. Tilemann, M. Heckmann, A. Jungmann, C. Vettel, H. A. Katus, A. El-Armouche, O. J. Müller (Heidelberg, Göttingen) |
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(P752) |
Cathepsin A – a novel target for pharmacological inhibition in various heart diseases? |
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M. Hohl, B. Linz, T. Hübschle, W. Linz, T. Sadowski, U. Schotten, M. Böhm, D. Linz (Homburg/Saar, Frankfurt am Main; Maastricht, NL) |