78. Jahrestagung der Deutschen Gesellschaft für Kardiologie

Donnerstag, 12. April 2012 (Saal 7) 11:00-12:30

Freie Vorträge

Mitochondrien bei Ischämie/Reperfusion

Vorsitz: H. Bugger (Freiburg im Breisgau), A. Gödecke (Düsseldorf)

(V478) Mitochondrial but not cytosolic thioredoxin reductase is essential for postischemic myocardial protection in mice via postischemic mitochondrial ROS-scavanging

P. Lange, J. C. Horstkotte, M. Schneider, M. Schröder, S. Schulz, R. Hinkel, C. Kiermayer, T. Ziegler, M. Brielmeier, H. Zischka, M. Conrad, C. Kupatt (München, Siegburg, Neuherberg)
(V479) Cardioprotection by Cyclosporine A is mediated by the inhibition of the mitochondrial permeability transition pore and not by improvement of mitochondrial respiration.

A. Skyschally, N. Gedik, B. Walter, G. Heusch (Essen)
(V480) Cx43 hemichannels of the inner mitochondrial membrane mediate ischemic preconditioning in murine cardiomyocytes

D. Rottländer, M. Wolny, L. J. Motloch, S. Reda, U. C. Hoppe (Salzburg, AT; Köln)
(V481) Proteinkinase C affects mitochondrial calcium uptake by regulation of mitochondrial calcium uniporter

L. J. Motloch, T. Gebing, D. Rottländer, M. Wolny, S. Reda, R. Larbig, U. C. Hoppe (Salzburg, AT; Köln)
(V482) Reversal of the mitochondrial transhydrogenase consumes NADPH during cardiac workload and triggers oxidative stress and maladaptive remodelling

A. Nickel, J. R. Löffler, J.-C. Reil, A. von Hardenberg, M. Kohlhaas, M. Hohl, A. Kazakov, B. Pasieka, I. Bogeski, R. Kappl, M. Hoth, M. Böhm, C. Maack (Homburg/Saar)
(V483) Organ-specific expression of mitochondrial transhydrogenase determines reactive oxygen species production in response to high workload

J. Becker, A. Nickel, M. Hohl, J. R. Löffler, A. von Hardenberg, I. Bogeski, R. Kappl, M. Hoth, C. Maack (Homburg/Saar)